Enhanced Cell Capture on Functionalized Graphene Oxide Nanosheets through Oxygen Clustering.

ABSTRACT: With the global rise in incidence of cancer and infectious diseases, there is a need for the development of techniques to diagnose, treat, and monitor these conditions. The ability to efficiently capture and isolate cells and other biomolecules from peripheral whole blood for downstream analyses is a necessary requirement. Graphene oxide (GO) is an attractive template nanomaterial for such biosensing applications. Favorable properties include its two-dimensional architecture and wide range of functionalization chemistries, offering significant potential to tailor affinity toward aromatic functional groups expressed in biomolecules of interest. However, a limitation of current techniques is that as-synthesized GO nanosheets are used directly in sensing applications, and the benefits of thei

SUBMITTER: Bardhan NM 

PROVIDER: S-EPMC5804333 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature