Visualization of 3 Distinct Retinal Plexuses by Projection-Resolved Optical Coherence Tomography Angiography in Diabetic Retinopathy.

ABSTRACT:

Importance

Projection artifacts in optical coherence tomography angiography (OCTA) blur the retinal vascular plexuses together and limit visualization of the individual plexuses.

Objective

To describe projection-resolved (PR) OCTA in eyes with diabetic retinopathy (DR) and healthy eyes.

Design, setting, and participants

In this case-control study, patients with DR and healthy controls were enrolled in this observational study from January 26, 2015, to December 4, 2015, at a tertiary academic center. Spectral-domain, 70-kHz OCT obtained 3 × 3-mm macular scans. The PR algorithm suppressed projection artifacts. A semiautomated segmentation algorithm divided PR-OCTA into superficial, intermediate, and deep retinal plexuses. Two masked graders examined 3-layer PR-OCTA and

SUBMITTER: Hwang TS 

PROVIDER: S-EPMC5805384 | biostudies-literature | 2016 Dec

REPOSITORIES: biostudies-literature