A Longitudinal Analysis of Peripapillary Choroidal Thinning in Healthy and Glaucoma Subjects.

ABSTRACT:

Purpose

To evaluate the rate of peripapillary choroidal thinning in glaucoma patients and healthy controls using spectral domain optical coherence tomography.

Design

Cohort study.

Methods

Participants from the multicenter African Descent and Glaucoma Evaluation Study and Diagnostic Innovations in Glaucoma Study were included. The San Diego Automated Segmentation Algorithm was used to automatically segment and measure peripapillary choroidal thickness (PCT) from circle scans centered on the optic nerve head. The rate of PCT thinning was calculated using mixed effects models.

Results

Two hundred ninety-seven eyes with a median follow-up of 2.6 years were included. At baseline, the global mean PCT was significantly thinner in glaucoma patients than healthy control

SUBMITTER: Mundae RS 

PROVIDER: S-EPMC5805594 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature