Apolipoprotein L1 and Chronic Kidney Disease Risk in Young Potential Living Kidney Donors.

ABSTRACT:

Objective

The aim of this study was to develop a novel chronic kidney disease (CKD) risk prediction tool for young potential living kidney donors.

Summary of background data

Living kidney donor selection practices have evolved from examining individual risk factors to a risk calculator incorporating multiple characteristics. Owing to limited long-term data and lack of genetic information, current risk tools lack precision among young potential living kidney donors, particularly African Americans (AAs).

Methods

We identified a cohort of young adults (18-30 years) with no absolute contraindication to kidney donation from the longitudinal cohort study Coronary Artery Risk Development in Young Adults. Risk associations for CKD (estimated glomerular filtration rate <60 mL/

SUBMITTER: Locke JE 

PROVIDER: S-EPMC5805656 | biostudies-literature | 2018 Jun

REPOSITORIES: biostudies-literature