Acute acetaminophen ingestion improves performance and muscle activation during maximal intermittent knee extensor exercise.

ABSTRACT:

Aim

Acetaminophen is a commonly used medicine for pain relief and emerging evidence suggests that it may improve endurance exercise performance. This study investigated some of the physiological mechanisms by which acute acetaminophen ingestion might blunt muscle fatigue development.

Methods

Thirteen active males completed 60 × 3 s maximum voluntary contractions (MVC) of the knee extensors with each contraction separated by a 2 s passive recovery period. This protocol was completed 60 min after ingesting 1 g of maltodextrin (placebo) or 1 g of acetaminophen on two separate visits. Peripheral nerve stimulation was administered every 6th contraction for assessment of neuromuscular fatigue development, with the critical torque (CT), which reflects the maximal sustainable rate o

SUBMITTER: Morgan PT 

PROVIDER: S-EPMC5805811 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature