Alterations in the inferior longitudinal fasciculus in autism and associations with visual processing: a diffusion-weighted MRI study.

ABSTRACT:

Background

One of the most reported neural features of autism spectrum disorder (ASD) is the alteration of multiple long-range white matter fiber tracts, as assessed by diffusion-weighted imaging and indexed by reduced fractional anisotropy (FA). Recent methodological advances, however, have shown that this same pattern of reduced FA may be an artifact resulting from excessive head motion and poorer data quality and that aberrant structural connectivity in children with ASD is confined to the right inferior longitudinal fasciculus (ILF). This study aimed at replicating the observation of reduced FA along the right ILF in ASD, while controlling for group differences in head motion and data quality. In addition, we explored associations between reduced FA in the right ILF and quantit

SUBMITTER: Boets B 

PROVIDER: S-EPMC5806238 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature