Proteomics analysis of faecal proteins in the tick Haemaphysalis flava.

ABSTRACT:

Background

Ticks and tick-borne diseases are of major public health concern. Currently, development of vaccines against ticks is considered crucial for their control. A critical step in this process is the screening of viable antigens. Faeces are byproducts of digestion and blood meal utilization, and partly reflect the vitality and vector potential of ticks. However, an integrated analysis of proteins in tick faeces is lacking. The present study explored the protein components in the faeces of the tick Haemaphysalis flava, by liquid chromatography-tandem mass spectrometry (LC/MS-MS) to identify potential protein antigens for vaccine development against ticks.

Methods

Faeces from adult H. flava engorged females were collected. Proteins were extracted from faeces, and the try

SUBMITTER: Liu L 

PROVIDER: S-EPMC5806362 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature