25-hydroxyvitamin D, influenza vaccine response and healthcare encounters among a young adult population.

ABSTRACT:

Background

Influenza causes significant morbidity and mortality; the pandemic in 2009-2010 was a reminder of the potential for novel strains and antigenic changes. Studies have shown that vitamin D deficiency may be associated with poor vaccine immunogenicity, therefore we sought to determine if there was a correlation between 25-hydroxyvitamin D [25(OH)D] and influenza vaccine response.

Methods

A retrospective observational study was conducted among young, healthy military members to evaluate the association between total 25(OH)D levels with post influenza vaccination antibody titers and healthcare encounters during the 2009-10 influenza season. Univariate analyses were performed to evaluate whether 25(OH)D levels are associated with baseline characteristics and post-vaccin

SUBMITTER: Lee RU 

PROVIDER: S-EPMC5806853 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature