Exposure of the lungs in breast cancer radiotherapy: A systematic review of lung doses published 2010-2015.

ABSTRACT:

Background and purpose

We report a systematic review of lung radiation doses from breast cancer radiotherapy.

Methods and materials

Studies describing breast cancer radiotherapy regimens published during 2010-2015 and reporting lung dose were included. Doses were compared between different countries, anatomical regions irradiated, techniques and use of breathing adaptation.

Results

471 regimens from 32 countries were identified. The average mean ipsilateral lung dose (MLD_ipsi) was 9.0 Gy. MLD_ipsi for supine radiotherapy with no breathing adaption was 8.4 Gy for whole breast/chest wall (WB/CW) radiotherapy, 11.2 Gy when the axilla/supraclavicular fossa was irradiated, and 14.0 Gy with the addition of internal mammary chain irradiation; breathing a

SUBMITTER: Aznar MC 

PROVIDER: S-EPMC5807032 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature