Clinicopathological Evaluation of Chronic Traumatic Encephalopathy in Players of American Football.

ABSTRACT:

Importance

Players of American football may be at increased risk of long-term neurological conditions, particularly chronic traumatic encephalopathy (CTE).

Objective

To determine the neuropathological and clinical features of deceased football players with CTE.

Design, setting, and participants

Case series of 202 football players whose brains were donated for research. Neuropathological evaluations and retrospective telephone clinical assessments (including head trauma history) with informants were performed blinded. Online questionnaires ascertained athletic and military history.

Exposures

Participation in American football at any level of play.

Main outcomes and measures

Neuropathological diagnoses of neurodegenerative diseases, including CTE, based on

SUBMITTER: Mez J 

PROVIDER: S-EPMC5807097 | biostudies-literature | 2017 Jul

REPOSITORIES: biostudies-literature