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Eye gaze perception in bipolar disorder: Self-referential bias but intact perceptual sensitivity.


ABSTRACT: OBJECTIVES:Deficits in social cognition predict poor functional outcome in severe mental illnesses such as schizophrenia and autism. However, research findings on social cognition in bipolar disorder (BD) are sparse and inconsistent. This study aimed to characterize a critical social cognitive process-eye gaze perception-and examine its functional correlates in BD to inform psychopathological mechanisms. METHODS:Thirty participants with BD, 37 healthy controls (HC), and 46 psychiatric controls with schizophrenia (SZ) completed an eye-contact perception task. They viewed faces with varying gaze directions, head orientations, and emotion, and made eye-contact judgments. Psychophysics methods were used to estimate perception thresholds and the slope of the perception curve, which were then co

SUBMITTER: Yao B 

PROVIDER: S-EPMC5807101 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature