Wastewater-based tracing of doping use by the general population and amateur athletes.

ABSTRACT: The present study investigates the applicability of the chemical analysis of wastewater to assess the use of doping substances by the general population and amateur athletes. To this end, an analytical methodology that can identify and quantify a list of 15 substances from the groups of anabolic steroids, weight loss products, and masking agents in wastewater has been developed. The method uses solid phase extraction to increase the detection sensitivity of the target analytes, expected to be present at very low concentrations (ng L^-1 range), and decrease possible matrix interferences. Instrumental analysis is performed by liquid chromatography coupled to high-resolution mass spectrometry, allowing data acquisition in both full scan and tandem MS mode. The method has been succes

SUBMITTER: Causanilles A 

PROVIDER: S-EPMC5807464 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature