Rapid intravenous rehydration of children with acute gastroenteritis and dehydration: a systematic review and meta-analysis.

ABSTRACT:

Background

The World Health Organization (WHO) recommends rapid intravenous rehydration, using fluid volumes of 70-100mls/kg over 3-6 h, with some of the initial volume given rapidly as initial fluid boluses to treat hypovolaemic shock for children with acute gastroenteritis (AGE) and severe dehydration. The evidence supporting the safety and efficacy of rapid versus slower rehydration remains uncertain.

Methods

We conducted a systematic review of randomised controlled trials (RCTs) on 11th of May 2017 comparing different rates of intravenous fluid therapy in children with AGE and moderate or severe dehydration, using standard search terms. Two authors independently assessed trial quality and extracted data. Non-RCTs and non-English articles were excluded. The primary endpoi

SUBMITTER: Iro MA 

PROVIDER: S-EPMC5807758 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature