Favourable prognostic role of histological regression in stage III positive sentinel lymph node melanoma patients.

ABSTRACT:

Background

Sentinel lymph node (SLN)-positive melanoma patients are a heterogeneous group of patients with survival rates ranging from ∼20 to over 80%. No data are reported concerning the role of histological regression on survival in stage III melanoma.

Methods

The study included 365 patients with positive SLN from two distinct hospitals. The model was developed on patients from 'AOU Città della Salute e della Scienza di Torino', and externally validated on patients from IRCCS of Candiolo. Survival analyses were carried out according to the presence of regression and adjusted for all other prognostic factors.

Results

Among patients followed at 'AOU Città della Salute e della Scienza di Torino' (n=264), the median follow-up time to death or censoring (whatever two eve

SUBMITTER: Zugna D 

PROVIDER: S-EPMC5808022 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature