Antitumor activity of Chlorella sorokiniana and Scenedesmus sp. microalgae native of Nuevo Leon State, Mexico.

ABSTRACT: Cancer cases result in 13% of all deaths worldwide. Unwanted side effects in patients under conventional treatments have led to the search for beneficial alternative therapies. Microalgae synthesize compounds with known in vitro and in vivo biological activity against different tumor cell lines. Therefore, native microalgae from the State of Nuevo Leon, Mexico may become a potential source of antitumor agents. The aim of the present study was to evaluate the in vitro cytotoxic effect of Nuevo Leon regional Chlorella sorokiniana (Chlorellales: Chlorellaceae) and Scenedesmus sp. (Chlorococcales: Scenedesmaceae). Native microalgae crude organic extracts cytotoxicity against murine L5178Y-R lymphoma cell line and normal lymphocyte proliferation were evaluated using the MTT reduction colorimetr

SUBMITTER: Reyna-Martinez R 

PROVIDER: S-EPMC5808310 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature