Recently integrated Alu insertions in the squirrel monkey (Saimiri) lineage and application for population analyses.

ABSTRACT:

Background

The evolution of Alu elements has been ongoing in primate lineages and Alu insertion polymorphisms are widely used in phylogenetic and population genetics studies. Alu subfamilies in the squirrel monkey (Saimiri), a New World Monkey (NWM), were recently reported. Squirrel monkeys are commonly used in biomedical research and often require species identification. The purpose of this study was two-fold: 1) Perform locus-specific PCR analyses on recently integrated Alu insertions in Saimiri to determine their amplification dynamics, and 2) Identify a subset of Alu insertion polymorphisms with species informative allele frequency distributions between the Saimiri sciureus and Saimiri boliviensis groups.

Results

SUBMITTER: Baker JN 

PROVIDER: S-EPMC5808450 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature