Functional Modification of Silica through Enhanced Adsorption of Elastin-Like Polypeptide Block Copolymers.

ABSTRACT: A powerful tool for controlling interfacial properties and molecular architecture relies on the tailored adsorption of stimuli-responsive block copolymers onto surfaces. Here, we use computational and experimental approaches to investigate the adsorption behavior of thermally responsive polypeptide block copolymers (elastin-like polypeptides, ELPs) onto silica surfaces, and to explore the effects of surface affinity and micellization on the adsorption kinetics and the resultant polypeptide layers. We demonstrate that genetic incorporation of a silica-binding peptide (silaffin R5) results in enhanced adsorption of these block copolymers onto silica surfaces as measured by quartz crystal microbalance and ellipsometry. We find that the silaffin peptide can also direct micelle adsorption, lead

SUBMITTER: Li L 

PROVIDER: S-EPMC5809277 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature