Drug-related deaths in hospital inpatients: A retrospective cohort study.

ABSTRACT:

Aims

To determine the incidence of drug-related deaths (DRD) in a university hospital in 2015, to describe their characteristics, and to discover risk factors of DRD.

Methods

An analytic and retrospective cohort study. Patients with a death diagnosed predefined from a list of medical conditions potentially caused by drugs were the selected cases for further review. Causality assessment was evaluated by a local drug safety committee.

Results

Out of 1135 inpatient deaths, 73 DRD were included (six were hospital-acquired). The incidence of DRD of all hospital admissions was 0.34%, and the incidence of all deaths cases was 7%. Drugs were the cause of death in 38 patients (52%) and a contributive role in 35 (48%). The median age of DRD patients was 72 years (range 19-94) a

SUBMITTER: Montane E 

PROVIDER: S-EPMC5809345 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature