Determination of hemodynamic risk for vascular disease in planar artery bifurcations.

ABSTRACT: Understanding hemodynamics in blood circulation is crucial in order to unveil the mechanisms underlying the formation of stenosis and atherosclerosis. In fact, there are experimental evidences pointing out to the existence of some given vessel configurations that are more likely to develop the above mentioned pathologies. Along this manuscript, we performed an exhaustive investigation in a simplified model aiming to characterize by means of physical quantities those regions and configurations in vessel bifurcations that are more likely to develop such pathologies. The two-fold analysis is based, on the one hand, on numerical simulations (via CFD) and, on the other hand, on experiments realized in an ad-hoc designed polydimethylsiloxane (PDMS) channel with the appropriate parameters and app

SUBMITTER: Otero-Cacho A 

PROVIDER: S-EPMC5809427 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature