International core outcome set for clinical trials of medication review in multi-morbid older patients with polypharmacy.

ABSTRACT:

Background

Comparisons of clinical trial findings in systematic reviews can be hindered by the heterogeneity of the outcomes reported. Moreover, the outcomes that matter most to patients might be underreported. A core outcome set can address these issues, as it defines a minimum set of outcomes that should be reported in all clinical trials in a particular area of research. The objective in this study was to develop a core outcome set for clinical trials of medication review in multi-morbid older patients with polypharmacy.

Methods

Firstly, eligible outcomes were identified through a systematic review of trials of medication review in older patients (≥65 years) and interviews with 15 older patients. Secondly, an international three-round Delphi survey in four countries invol

SUBMITTER: Beuscart JB 

PROVIDER: S-EPMC5809844 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature