Lactobacillus fermentum 3872 as a potential tool for combatting Campylobacter jejuni infections.

ABSTRACT: Due to the global spread of multidrug resistant pathogenic bacteria, alternative approaches in combating infectious diseases are required. One such approach is the use of probiotics. Lactobacillus fermentum 3872 is a promising probiotic bacterium producing a range of antimicrobial compounds, such as hydrogen peroxide and lactic acid. In addition, previous studies involving genome sequencing and analysis of L. fermentum 3872 allowed the identification of a gene encoding a cell surface protein referred to as collagen binding protein (CBP) (not found in other strains of the species, according to the GenBank database), consisting of a C-terminal cell wall anchor domain (LPXT), multiple repeats of 'B domains' that form stalks presenting an "A domain" required for adhesion. In this study, we fou

SUBMITTER: Lehri B 

PROVIDER: S-EPMC5810503 | biostudies-literature | 2017 Nov

REPOSITORIES: biostudies-literature