Variability in metagenomic samples from the Puget Sound: Relationship to temporal and anthropogenic impacts.

ABSTRACT: Whole-metagenome sequencing (WMS) has emerged as a powerful tool to assess potential public health risks in marine environments by measuring changes in microbial community structure and function in uncultured bacteria. In addition to monitoring public health risks such as antibiotic resistance determinants, it is essential to measure predictors of microbial variation in order to identify natural versus anthropogenic factors as well as to evaluate reproducibility of metagenomic measurements.This study expands our previous metagenomic characterization of Puget Sound by sampling new nearshore environments including the Duwamish River, an EPA superfund site, and the Hood Canal, an area characterized by highly variable oxygen levels. We also resampled a wastewater treatment plant, nearshore and

SUBMITTER: Wallace JC 

PROVIDER: S-EPMC5811002 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature