Entropy driven chain effects on ligation chemistry.

ABSTRACT: We report the investigation of fundamental entropic chain effects that enable the tuning of modular ligation chemistry - for example dynamic Diels-Alder (DA) reactions in materials applications - not only classically via the chemistry of the applied reaction sites, but also via the physical and steric properties of the molecules that are being joined. Having a substantial impact on the reaction equilibrium of the reversible ligation chemistry, these effects are important when transferring reactions from small molecule studies to larger or other entropically very dissimilar systems. The effects on the DA equilibrium and thus the temperature dependent degree of debonding (%_debond) of different cyclopentadienyl (di-)functional poly(meth-)acrylate backbones (poly(methy

SUBMITTER: Pahnke K 

PROVIDER: S-EPMC5811146 | biostudies-literature | 2015 Feb

REPOSITORIES: biostudies-literature