A data-driven approach for addressing the lack of flow waveform data in studies of cerebral arterial flow in older adults.

ABSTRACT: OBJECTIVE:Blood flow waveforms-essential data for hemodynamic modeling-are often in practice unavailable to researchers. The objectives of this work were to assess the variability among the waveforms for a clinically relevant older population, and develop data-based methods for addressing the missing waveform data for hemodynamic studies. APPROACH:We analyzed 272 flow waveforms from the internal carotid arteries of older patients (73  ±  13 yr) with moderate cardiovascular disease, and used these data to develop methods to guide new approaches for hemodynamic studies. MAIN RESULTS:Profound variations in waveform parameters were found within the aged population that were not seen in published data for young subjects. Common features in the aged population relative to the young included a la

SUBMITTER: Durka MJ 

PROVIDER: S-EPMC5811231 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature