Temporally resolved parametric assessment of Z-magnetization recovery (TOPAZ): Dynamic myocardial T₁ mapping using a cine steady-state look-locker approach.

ABSTRACT:

Purpose

To develop and evaluate a cardiac phase-resolved myocardial T₁ mapping sequence.

Methods

The proposed method for temporally resolved parametric assessment of Z-magnetization recovery (TOPAZ) is based on contiguous fast low-angle shot imaging readout after magnetization inversion from the pulsed steady state. Thereby, segmented k-space data are acquired over multiple heartbeats, before reaching steady state. This results in sampling of the inversion-recovery curve for each heart phase at multiple points separated by an R-R interval. Joint T₁ and B1+ estimation is performed for reconstruction of cardiac phase-resolved T₁ and B1+ maps. Sequence parameters are optimized using numerical simulations. Phantom and in vivo imaging are performe

SUBMITTER: Weingartner S 

PROVIDER: S-EPMC5811329 | biostudies-literature | 2018 Apr

REPOSITORIES: biostudies-literature