Longitudinal changes in global and domain specific cognitive function in the very-old: findings from the Newcastle 85+ Study.

ABSTRACT:

Objective

Ageing is associated with changes in cognition in some, but not all domains. In young-old adults, defined as persons aged 65-84 years, baseline cognitive function has been shown to impact on cognitive trajectories. Whether similar patterns occur in the very-old, defined as persons aged 85 years and over, is not known.

Methods

Longitudinal changes (5 years' follow-up) in global and domain specific cognitive function including memory, attention and speed were investigated in participants from the Newcastle 85+ Study (n = 845). At baseline, participants were grouped using Mini-Mental State Examination cut-off scores and dementia status into the following: not impaired, mildly impaired or severely impaired/dementia groups.

Results

Only a limited number of cognit

SUBMITTER: Stephan BCM 

PROVIDER: S-EPMC5811803 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature