Characteristics of people with high visit-to-visit glycaemic variability in Type 2 diabetes.

ABSTRACT:

Aims

Increased visit-to-visit glycaemic variability is independently associated with adverse outcomes in Type 2 diabetes. Our aim was to identify the patient characteristics associated with raised visit-to-visit glycaemic variability in people with Type 2 diabetes.

Methods

A case-control study was conducted to establish associations between HbA_1c variability and clinical covariates in 10 130 people with Type 2 diabetes. Variability was calculated by two metrics [sd and coefficient of variation (CV)] from a minimum of four HbA_1c readings obtained over a 4-year period. High and low variability groups were defined as the top and bottom tertile of the sd or CV, and used in logistic regression analyses including a number of clinical and biochemical covariate

SUBMITTER: Noyes JD 

PROVIDER: S-EPMC5811920 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature