Stereotactic Body Radiotherapy (SBRT) for liver metastasis - clinical outcomes from the international multi-institutional RSSearch® Patient Registry.

ABSTRACT:

Background

Stereotactic body radiotherapy (SBRT) is an emerging treatment option for liver metastases in patients unsuitable for surgery. We investigated factors associated with clinical outcomes for liver metastases treated with SBRT from a multi-center, international patient registry.

Methods

Patients with liver metastases treated with SBRT were identified in the RSSearch® Patient Registry. Patient, tumor and treatment characteristics associated with treatment outcomes were assessed. Dose fractionations were normalized to BED₁₀. Overall survival (OS) and local control (LC) were evaluated using Kaplan Meier analysis and log-rank test.

Results

The study included 427 patients with 568 liver metastases from 25 academic and community-based centers. Median age

SUBMITTER: Mahadevan A 

PROVIDER: S-EPMC5811977 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature