Genome-wide scan for commons SNPs affecting bovine leukemia virus infection level in dairy cattle.

ABSTRACT:

Background

Bovine leukemia virus (BLV) infection is omnipresent in dairy herds causing direct economic losses due to trade restrictions and lymphosarcoma-related deaths. Milk production drops and increase in the culling rate are also relevant and usually neglected. The BLV provirus persists throughout a lifetime and an inter-individual variation is observed in the level of infection (LI) in vivo. High LI is strongly correlated with disease progression and BLV transmission among herd mates. In a context of high prevalence, classical control strategies are economically prohibitive. Alternatively, host genomics studies aiming to dissect loci associated with LI are potentially useful tools for genetic selection programs tending to abrogate the viral spreading. The LI was measured throu

SUBMITTER: Carignano HA 

PROVIDER: S-EPMC5812220 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature