Alpha desynchronization/synchronization during working memory testing is compromised in acute mild traumatic brain injury (mTBI).

ABSTRACT: Diagnosing and monitoring recovery of patients with mild traumatic brain injury (mTBI) is challenging because of the lack of objective, quantitative measures. Diagnosis is based on description of injuries often not witnessed, subtle neurocognitive symptoms, and neuropsychological testing. Since working memory (WM) is at the center of cognitive functions impaired in mTBI, this study was designed to define objective quantitative electroencephalographic (qEEG) measures of WM processing that may correlate with cognitive changes associated with acute mTBI. First-time mTBI patients and mild peripheral (limb) trauma controls without head injury were recruited from the emergency department. WM was assessed by a continuous performance task (N-back). EEG recordings were obtained during N-back testin

SUBMITTER: Arakaki X 

PROVIDER: S-EPMC5812562 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature