Oasis 2: improved online analysis of small RNA-seq data.

ABSTRACT:

Background

Small RNA molecules play important roles in many biological processes and their dysregulation or dysfunction can cause disease. The current method of choice for genome-wide sRNA expression profiling is deep sequencing.

Results

Here we present Oasis 2, which is a new main release of the Oasis web application for the detection, differential expression, and classification of small RNAs in deep sequencing data. Compared to its predecessor Oasis, Oasis 2 features a novel and speed-optimized sRNA detection module that supports the identification of small RNAs in any organism with higher accuracy. Next to the improved detection of small RNAs in a target organism, the software now also recognizes potential cross-species miRNAs and viral and bacterial sRNAs in infected sam

SUBMITTER: Rahman RU 

PROVIDER: S-EPMC5813365 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature