Differential expression of mRNA isoforms in the skeletal muscle of pigs with distinct growth and fatness profiles.

ABSTRACT:

Background

The identification of genes differentially expressed in the skeletal muscle of pigs displaying distinct growth and fatness profiles might contribute to identify the genetic factors that influence the phenotypic variation of such traits. So far, the majority of porcine transcriptomic studies have investigated differences in gene expression at a global scale rather than at the mRNA isoform level. In the current work, we have investigated the differential expression of mRNA isoforms in the gluteus medius (GM) muscle of 52 Duroc HIGH (increased backfat thickness, intramuscular fat and saturated and monounsaturated fatty acids contents) and LOW pigs (opposite phenotype, with an increased polyunsaturated fatty acids content).

Results

Our analysis revealed that 10.9% of

SUBMITTER: Cardoso TF 

PROVIDER: S-EPMC5813380 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature