Addressing the selective role of distinct prefrontal areas in response suppression: A study with brain tumor patients.

ABSTRACT: The diverging evidence for functional localization of response inhibition within the prefrontal cortex might be justified by the still unclear involvement of other intrinsically related cognitive processes like response selection and sustained attention. In this study, the main aim was to understand whether inhibitory impairments, previously found in patients with both left and right frontal lesions, could be better accounted for by assessing these potentially related cognitive processes. We tested 37 brain tumor patients with left prefrontal, right prefrontal and non-prefrontal lesions and a healthy control group on Go/No-Go and Foreperiod tasks. In both types of tasks inhibitory impairments are likely to cause false alarms, although additionally the former task requires response selectio

SUBMITTER: Arbula S 

PROVIDER: S-EPMC5813715 | biostudies-literature | 2017 Jun

REPOSITORIES: biostudies-literature