Possible mechanism underlying the association between height and vascular remodeling in elderly Japanese men.

ABSTRACT: Height is reported to be inversely associated with cardiovascular disease. And platelets play an important role in vascular remodeling by supporting CD34-positive cells. To clarify the association between height and platelet, we conducted a cross-sectional study of 219 elderly Japanese men. Since hemoglobin concentration is influenced by vascular remodeling activity, an analysis stratified by hemoglobin level was performed. An inverse association was seen between height and platelet count in subjects with a high hemoglobin concentration (≥ 14.5 g/dL), but not in subjects with a low hemoglobin concentration (< 14.5 g/dL). The standardized parameter estimates (β) were β = -0.22, p = 0.019 for subjects with high hemoglobin, and β = -0.01, p = 0.931 for subjects with low hemoglob

SUBMITTER: Shimizu Y 

PROVIDER: S-EPMC5814254 | biostudies-literature | 2018 Jan

REPOSITORIES: biostudies-literature