Kinesthetic stimulation for obstructive sleep apnea syndrome: An "on-off" proof of concept trial.

ABSTRACT: Obstructive sleep apnea (OSA) occurs when the upper airway narrows or collapses due to the loss of upper airway muscle activation at sleep onset. This study investigated the effectiveness of triggered kinesthetic stimulation in patients with OSA. This proof-of-concept, open-label, multicenter prospective study was conducted on 24 patients with severe OSA. During a one night evaluation, kinesthetic stimulation was intermittently delivered in 30 minute periods. The duration of apneas and hypopneas during Stim _on and Stim _off periods were compared. Five hospital-based university centers in France participated. Sleep studies were evaluated by a single scorer at a core laboratory (CHU Grenoble). Results show that during the Stim _on phases, statistically signific

SUBMITTER: Hernandez AI 

PROVIDER: S-EPMC5814419 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature