The centrality of DSM and non-DSM depressive symptoms in Han Chinese women with major depression.

ABSTRACT:

Introduction

We compared DSM-IV criteria for major depression (MD) with clinically selected non-DSM criteria in their ability to represent clinical features of depression.

Method

We conducted network analyses of 19 DSM and non-DSM symptoms of MD assessed at personal interview in 5952 Han Chinese women meeting DSM-IV criteria for recurrent MD. We estimated an Ising model (the state-of-the-art network model for binary data), compared the centrality (interconnectedness) of DSM-IV and non-DSM symptoms, and investigated the community structure (symptoms strongly clustered together).

Results

The DSM and non-DSM criteria were intermingled within the same symptom network. In both the DSM-IV and non-DSM criteria sets, some symptoms were central (highly interconnected) while ot

SUBMITTER: Kendler KS 

PROVIDER: S-EPMC5815309 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature