ECoG high-gamma modulation versus electrical stimulation for presurgical language mapping.

ABSTRACT:

Objective

This meta-analysis compared diagnostic validity of electrocorticographic (ECoG) high-γ modulation (HGM) with electrical stimulation mapping (ESM) for presurgical language localization.

Methods

From a structured literature search, studies with electrode level data comparing ECoG HGM and ESM for language localization were included in the meta-analysis. Outcomes included global measures of diagnostic validity: area under the summary receiver operating characteristic (SROC) curve (AUC), and diagnostic odds ratio (DOR); as well as pooled estimates of sensitivity and specificity. Clinical and technical determinants of sensitivity/specificity were explored.

Results

Fifteen studies were included in qualitative synthesis, and 10 studies included in the meta-analysis

SUBMITTER: Arya R 

PROVIDER: S-EPMC5815885 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature