C-Reactive protein in relation to fecundability and anovulation among eumenorrheic women.

ABSTRACT:

Objective

To assess systemic inflammation in relation to fecundability and anovulation.

Design

Prospective cohort study among participants in the Effects of Aspirin in Gestation and Reproduction trial who were assigned to the placebo.

Setting

Academic medical centers.

Patient(s)

Healthy eumenorrheic women (n = 572), 18-40 years of age, with one or two pregnancy losses, attempting spontaneous pregnancy.

Intervention(s)

Baseline serum high-sensitivity C-reactive protein (hsCRP) values <10 mg/L were categorized into tertiles.

Main outcome measure(s)

Discrete Cox proportional hazards models estimated the fecundability odds ratio (FOR) and 95% confidence interval (CI) and adjusted for potential confounders. Log-binomial regression estimated the risk ra

SUBMITTER: Radin RG 

PROVIDER: S-EPMC5815923 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature