Disruption to functional networks in neonates with perinatal brain injury predicts motor skills at 8 months.

ABSTRACT:

Objective

Functional connectivity magnetic resonance imaging (fcMRI) of neonates with perinatal brain injury could improve prediction of motor impairment before symptoms manifest, and establish how early brain organization relates to subsequent development. This cohort study is the first to describe and quantitatively assess functional brain networks and their relation to later motor skills in neonates with a diverse range of perinatal brain injuries.

Methods

Infants (n = 65, included in final analyses: n = 53) were recruited from the neonatal intensive care unit (NICU) and were stratified based on their age at birth (premature vs. term), and on whether neuropathology was diagnosed from structural MRI. Functional brain networks and a measure of disruption to fu

SUBMITTER: Linke AC 

PROVIDER: S-EPMC5816024 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature