Functional status mediates the association between peripheral neuropathy and health-related quality of life in individuals with diabetes.

ABSTRACT:

Aims

To examine differences in health-related quality of life (HRQoL) between patients with and without diabetic peripheral neuropathy (DPN), and whether these differences can be explained by functional deficits.

Methods

This was a cross-sectional study of 160 patients with type 2 diabetes mellitus, 80 with DPN and 80 without. Assessments included HRQoL (health utility score derived from EQ-5D-5L), functional status measurements [muscle strength, timed up and go (TUG), five times sit-to-stand (FTSTS), functional reach, body sway velocity] and self-reported balance confidence [Activities-specific Balance Confidence (ABC) scale].

Results

Mean utility scores were 0.67 ± 0.14 and 0.77 ± 0.16 in patients with and without DPN, respectively (p < 0.001). Patients with DPN had

SUBMITTER: Riandini T 

PROVIDER: S-EPMC5816102 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature