Heterogeneity within the frontoparietal control network and its relationship to the default and dorsal attention networks.

ABSTRACT: The frontoparietal control network (FPCN) plays a central role in executive control. It has been predominantly viewed as a unitary domain general system. Here, we examined patterns of FPCN functional connectivity (FC) across multiple conditions of varying cognitive demands, to test for FPCN heterogeneity. We identified two distinct subsystems within the FPCN based on hierarchical clustering and machine learning classification analyses of within-FPCN FC patterns. These two FPCN subsystems exhibited distinct patterns of FC with the default network (DN) and the dorsal attention network (DAN). FPCN_A exhibited stronger connectivity with the DN than the DAN, whereas FPCN_B exhibited the opposite pattern. This twofold FPCN differentiation was observed across four independent

SUBMITTER: Dixon ML 

PROVIDER: S-EPMC5816169 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature