High risk human papillomavirus prevalence and genotype distribution among women infected with HIV in Manaus, Amazonas.

ABSTRACT:

Background

Human immunodeficiency virus (HIV)-positive women have a high prevalence of human papillomavirus (HPV), and are infected with a broader range of HPV types than HIV-negative women. We aimed to determine the prevalence of cervical cytologic abnormalities, high-risk (HR)-HPV prevalence, type distribution according to the severity of cervical lesions and CD4 cell count and identify factors associated with HR-HPV infection among women living with HIV in Manaus, Amazonas.

Methods

We enrolled 325 women living with HIV that attended an infectious diseases referral hospital. Each woman underwent a gynecological exam, cervical cytology, HR-HPV detection by Polymerase chain Reaction (PCR) using the BD Onclarity™ HPV Assay, colposcopy and biopsy, when necessary. We assessed t

SUBMITTER: Teixeira MF 

PROVIDER: S-EPMC5816532 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature