Fluid therapy and outcome: a prospective observational study in 65 German intensive care units between 2010 and 2011.

ABSTRACT:

Background

Outcome data on fluid therapy in critically ill patients from randomised controlled trials may be different from data obtained by observational studies under "real-life" conditions. We conducted this prospective, observational study to investigate current practice of fluid therapy (crystalloids and colloids) and associated outcomes in 65 German intensive care units (ICUs). In total, 4545 adult patients who underwent intravenous fluid therapy were included. The main outcome measures were 90-day mortality, ICU mortality and acute kidney injury (AKI). Data were analysed using logistic and Cox regression models, as appropriate.

Results

In the predominantly post-operative overall cohort, unadjusted 90-day mortality was 20.1%. Patients who also received colloids (54.6%)

SUBMITTER: Ertmer C 

PROVIDER: S-EPMC5816732 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature