Seizure semiology: an important clinical clue to the diagnosis of autoimmune epilepsy.

ABSTRACT:

Objective

The purpose of this study is to analyze the seizure semiologic characteristics of patients with autoimmune epilepsy (AE) and describe the investigation characteristics of AE using a larger sample size.

Methods

This observational retrospective case series study was conducted from a tertiary epilepsy center between May 2014 and March 2017. Cases of new-onset seizures were selected based on laboratory evidence of autoimmunity. At the same time, typical mesial temporal lobe epilepsy (MTLE) patients with hippocampal sclerosis (HS) were recruited as the control group from the subjects who underwent presurgical evaluation during the same period.

Results

A total of 61 patients with AE were identified. Specific autoimmune antibodies were detected in 39 patients (63.9

SUBMITTER: Lv RJ 

PROVIDER: S-EPMC5817820 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature