Association of Blood Transfusion From Female Donors With and Without a History of Pregnancy With Mortality Among Male and Female Transfusion Recipients.

ABSTRACT:

Importance

Transfusion of red blood cells from female donors has been associated with increased mortality in male recipients.

Objective

To quantify the association between red blood cell transfusion from female donors with and without a history of pregnancy and mortality of red blood cell recipients.

Design, setting, and participants

Retrospective cohort study of first-time transfusion recipients at 6 major Dutch hospitals enrolled from May 30, 2005, to September 1, 2015; the final follow-up date was September 1, 2015. The primary analysis was the no-donor-mixture cohort (ie, either all red blood cell transfusions exclusively from male donors, or all exclusively from female donors without a history of pregnancy, or all exclusively from female donors with a history of

SUBMITTER: Caram-Deelder C 

PROVIDER: S-EPMC5817970 | biostudies-literature | 2017 Oct

REPOSITORIES: biostudies-literature