Plasma Leptin and Reduced FEV₁ and FVC in Chronic Spinal Cord Injury.

ABSTRACT:

Background

Adipose tissue produces leptin, which is pro-inflammatory, and adiponectin, which has anti-inflammatory properties. Participants with chronic spinal cord injury (SCI) have increased body fat and are at increased risk for respiratory illness.

Objective

To assess the associations between leptin and adiponectin with pulmonary function in a chronic SCI cohort.

Design

Cross-sectional study.

Setting

Veterans Affairs Medical Center.

Participants

A total of 285 participants (237 men and 48 women) with chronic SCI with mean (standard deviation) injury duration 17.8 (13.2) years from the VA Boston and the community participating in an epidemiologic study assessing factors associated with respiratory health.

Methods

Participants (24.6% cervical Am

SUBMITTER: Garshick E 

PROVIDER: S-EPMC5818318 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature