Which attributes of whole genome sequencing tests are most important to the general population? Results from a German preference study.

ABSTRACT:

Objective

The aim of this study was to identify the preferences for whole genome sequencing (WGS) tests without genetic counseling.

Methods

A discrete choice experiment was conducted where participants chose between two hypothetical alternatives consisting of the following attributes: test accuracy, test costs, identified diseases, probability of disease occurrence, and data access. People from the general German population aged ≥18 years were eligible to participate in the survey. We estimated generalized linear mixed effects models, latent class mixed-logit models, and the marginal willingness to pay.

Results

Three hundred and one participants were included in the final analysis. Overall, the most favored WGS testing attributes were 95% test accuracy, report of seve

SUBMITTER: Plothner M 

PROVIDER: S-EPMC5818841 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature