FTO genotype, dietary protein intake, and body weight in a multiethnic population of young adults: a cross-sectional study.

ABSTRACT:

Background

Variation in the fat mass and obesity-associated gene (FTO) has been associated with susceptibility to obesity, but the association appears to be modified by diet. We investigated whether dietary protein intake modifies the association between FTO variant rs1558902 and body mass index (BMI) and waist circumference in young adults (n = 1491) from the cross-sectional Toronto Nutrigenomics and Health Study.

Results

Lifestyle, genetic, anthropometric, and biochemical data were collected and diet was assessed using a Toronto-modified Willett Food Frequency Questionnaire. General linear models stratified by ethnicity and adjusted for age, sex, and total energy intake were used to examine the association between FTO genotypes and measures of body wei

SUBMITTER: Merritt DC 

PROVIDER: S-EPMC5819260 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature