Continued in vitro cefazolin susceptibility in methicillin-susceptible Staphylococcus aureus.

ABSTRACT:

Objectives

In vitro trends of cefazolin and ceftriaxone susceptibilities from pediatric clinical isolates of methicillin-susceptible Staphylococcus aureus (MSSA) between 2011 and 2016 were analyzed for surveillance.

Methods

Our laboratory continues to use agar disk diffusion for staphylococcal susceptibilities applying Clinical Laboratory Standard Institute's 2012 breakpoints.

Results

A total of 3992 MSSA clinical isolates in the last 6 years were analyzed for their in vitro cefazolin and ceftriaxone susceptibilities. While all MSSA isolates exhibited cefazolin susceptibilities within the "susceptible" zone range, there have been a proportion of isolates with ceftriaxone susceptibilities falling in "intermediate" zones, ranging from 2.6% in 2011 to 8.3% in 2016.

Co

SUBMITTER: Gern BH 

PROVIDER: S-EPMC5819674 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature