Cardiorespiratory fitness is associated with enhanced hippocampal functional connectivity in healthy young adults.

ABSTRACT: Consistent associations have been found between higher cardiorespiratory fitness (CRF) and indices of enhanced brain health and function, including behavioral measures of cognition as well as neuroimaging indicators such as regional brain volume. Several studies have reported that higher CRF levels are associated with a larger hippocampus, yet associations between volume and memory or functional connectivity metrics remain poorly understood. Using a multi-modal framework, we hierarchically examine the association between CRF and hippocampal volume and resting state functional connectivity (rsFC) in younger adults, as well as their relationship between with memory function. We conducted theoretically-driven analyses with seeds in the anterior and posterior hippocampus, as well as control se

SUBMITTER: Stillman CM 

PROVIDER: S-EPMC5820159 | biostudies-literature | 2018 Mar

REPOSITORIES: biostudies-literature